Science, Whole Genome Sequencing

We read all3.2 billion letters of your DNA

Most genetic tests read fewer than 0.1% of your genome, a fixed panel of preset markers. Whole Genome Sequencing reads all of it, at 30× depth, so nothing actionable is missed and your data can be reanalysed for life as the science advances. One saliva sample. A reference for the rest of your life.

3.2Bbase pairs read
30×average sequencing depth
99.9%base call accuracy
1sample, reanalysed for life

A DNA double helix rendered in blue light

How your Genome is Read

From a saliva sample to a clinical grade report, every step is quality controlled in an accredited lab.

01Sample collection

You give a simple saliva sample at home with the prepaid kit. DNA is stabilised for transport and logged the moment it reaches the lab.

02Library prep and sequencing

Your DNA is fragmented, barcoded and sequenced on next generation platforms at 30× average depth, every region of the genome is read many times over for confidence.

03Bioinformatics and variant calling

Billions of short reads are aligned to a reference genome. Our pipeline calls single nucleotide variants, insertions, deletions and structural changes, then filters for quality.

04Clinical interpretation

Variants are annotated against curated clinical databases and reviewed against ACMG guidance, then written up in plain English with clear, actionable next steps.

What your Genome could reveal

Whole Genome Sequencing can give insight into six key areas of your health. Which ones you see depends on the test you choose.

Disease predisposition

Your inherited risk across cardiovascular, metabolic, neurological, immune and cancer related conditions, so you can screen earlier and act sooner.

Carrier status

Whether you carry variants for 300+ recessive and X-linked conditions you could pass on, essential when planning a family.

Pharmacogenomics

How your body activates and clears common medications, so prescribing can be tailored and adverse reactions avoided.

Traits and wellness

The genetics behind sleep, nutrition, fitness response, caffeine metabolism, injury risk and more.

Ancestry and composition

A deep genomic breakdown of your ancestral origins across global populations.

Rare, actionable findings

Clinically significant variants flagged under ACMG secondary findings guidance, for you and your clinician.

Why Whole Genome, not a chip

The genotyping chips behind most consumer DNA kits read a tiny, fixed set of positions. Whole Genome Sequencing reads everything.

Genotyping chip

Reads ~0.02% of your genome, a fixed panel of preset positions.
Blind to rare and novel variants that aren’t on the chip.
Can’t detect most structural or insertion/deletion changes.
Fixed forever, no reanalysis as science advances.

Whole Genome Sequencing

Reads all 3.2 billion base pairs at 30× depth.
Finds rare, novel and clinically actionable variants.
Captures SNVs, indels and structural variation.
Reanalysed for life from the same sample, no retest.

Lanes of sequenced DNA glowing under blue light, a pipette tip above them

Accuracy you can Trust

30× Depth

Every base is read many times over, so calls are made with high confidence.

Accredited Lab

Sequencing and interpretation run under recognised clinical lab quality standards.

Confirmed Findings

Key clinical variants are orthogonally validated before they reach your report.

Clinician Reviewed

Reports are reviewed against ACMG guidance by qualified scientists.

Your Data, Your Control

Encrypted in transit and at rest
Your genome is stored encrypted and access is tightly controlled.
Never sold
We never sell your genetic data or share it without your explicit consent.
Delete anytime
Withdraw consent and have your data and sample destroyed whenever you choose.